Table 3 Univariate Cox regression analysis of clinical factor and volume measurement with OS and PFS
From: Volumetric and MGMT parameters in glioblastoma patients: Survival analysis
| Â | Overall Survival | Progression-free Survival | ||||
|---|---|---|---|---|---|---|
| Â | HR | 95% CI | p | HR | 95% CI | p |
Sex | Â | Â | Â | Â | Â | Â |
   Female | 1 |  |  | 1 |  |  |
   Male | 1.18 | 0.69-2.02 | 0.538 | 1.32 | 0.79-2.23 | 0.289 |
Age | Â | Â | Â | Â | Â | Â |
   < 50 | 1 |  |  | 1 |  |  |
   ≥ 50 | 1.54 | 0.83-2.89 | 0.174 | 1.43 | 0.77-2.67 | 0.259 |
PS | Â | Â | Â | Â | Â | Â |
   0 | 1 |  |  | 1 |  |  |
   1 or 2 | 2.27 | 1.33-3.86 | 0.003 | 2.45 | 1.46-4.13 | 0.001 |
Surgery | Â | Â | Â | Â | Â | Â |
   Partial/Biopsy | 1 |  |  | 1 |  |  |
   Subtotal | 2.02 | 0.95-4.32 | 0.069 | 0.96 | 0.53-1.73 | 0.881 |
   Total | 1.33 | 0.68-2.60 | 0.409 | 0.70 | 0.33-1.48 | 0.352 |
Volumetry | Â | Â | Â | Â | Â | Â |
   PreOp Enhancing tumor | 1.01 | 1.00-1.02 | 0.037 | 1.01 | 1.00-1.02 | 0.041 |
   PreOp T2 abnormality | 1.00 | 1.00-1.01 | 0.276 | 1.00 | 1.00-1.01 | 0.387 |
   PreOp Necrosis | 1.02 | 1.00-1.04 | 0.067 | 1.02 | 1.00-1.05 | 0.021 |
   PreRCT Net-enhancing tumor | 1.02 | 1.01-1.04 | 0.001 | 1.01 | 1.00-1.02 | 0.068 |