Figure 6

Cell cycle progression in MEF ^tg2-/- and MCF-7 breast cancer cells overexpressing TG2 and m-TG2. Cell cycle distribution is shown in MEF^tg2-/- (left panel) and MCF-7 breast cancer cells (right panel). Cells at 60% confluency show an enhanced relative distribution in the S phase in TG2 overexpressing cells and a reduced relative distribution in the S phase in m-TG2 overexpressing cells (upper panels and table at bottom). The experiment was repeated three times. The table shows the mean ± SEM as a percentage for three independent experiments.