| |
rs1256049
| | |
rs4986938
|
|---|
| |
CC (Ref.a)
|
CT/TT
| |
CC (Ref.a)
|
CT/TT
| |
|---|
|
Subgroups
|
Ca/Cob
|
Ca/Cob
|
ORc (95% CI)
|
Ca/Cob
|
Ca/Cob
|
ORc (95% CI)
|
|---|
|
Age, years
|
|
≤ 48
|
30/88
|
50/150
|
1.0 (0.5–1.8)
|
55/186
|
27/49
|
1.4 (0.7–2.7)
|
|
>48
|
138/79
|
165/124
|
0.7 (0.5–1.0)
|
222/163
|
82/39
|
1.5 (0.9–2.3)
|
|
P
interaction
| | |
0.483
| | |
0.831
|
|
Ever
|
88/104
|
87/175
|
0.5 (0.4–0.8)
|
139/226
|
40/53
|
1.0 (0.6–1.7)
|
|
Never
|
80/63
|
128/162
|
1.0 (0.6–1.6)
|
138/123
|
69/35
|
2.2 (1.3–4.0)
|
|
P
interaction
| | |
0.061
| | |
0.058
|
|
Alcohol drinking status
|
|
Ever
|
66/112
|
66/178
|
0.6 (0.4–1.0)
|
100/229
|
34/57
|
1.6 (0.9–2.7)
|
|
Never
|
89/123
|
55/96
|
0.8 (0.5–1.2)
|
148/120
|
66/31
|
1.5 (0.9–2.4)
|
|
P
interaction
| | |
0.473
| | |
0.651
|
-
aRef. = reference group.
-
bCa/Co = colorectal cancer cases/controls.
-
cORs were calculated using unconditional logistic regression model adjusted for age, smoking status and alcohol drinking status.
