Clinical Settings (study numbers) [analysis model] | Mean Sen & (95% CI) | Mean Spe & (95% CI) | Mean DOR & (95% CI) | Mean LR + & (95% CI) | Mean LR- & (95% CI) | AUC & (95% CI) |
---|---|---|---|---|---|---|
EOC (n = 6) [bi] | 0.89 (0.84-0.93) | 0.83 (0.77-0.88) | 41.43 (26.17-65.57) | 5.25 (3.85-7.16) | 0.13 (0.08-0.20) | 0.93 (0.90-0.95)= |
[I2 =71.6%] | [I2 =80.7%] | [I2 =44.2%] | [I2 =75.7%] | [I2 =71.6%] | ||
EOC- preM (n = 5) [bi] | 0.82 (0.67-0.91) | 0.82 (0.74-0.88) | 20.55 (9.70-43.53) | 4.50 (3.19-6.36) | 0.22 (0.12-0.42) | 0.88 (0.85-0.91) ● |
[I2 =60.1%] | [I2 =74.8%] | [I2 =43.3%] | [I2 =66.0%] | [I2 =62.5%] | ||
EOC- postM (n = 5) [bi] | 0.93 (0.89-0.96) ▴ | 0.79 (0.73-0.83) | 47.27 (27.34-81.73) | 4.33 (3.41-5.50) | 0.09 (0.06-0.15) | 0.89 (0.86-0.92) ● |
[I2 =51.6%] | [I2 =16.2%] | [I2 =0.0%] | [I2 =15.6%] | [I2 =45.8%] | ||
EOC- early stage (n = 3) [uni] | 0.81 (0.71-0.89) ●= | 0.76 (0.73-0.79) ● | 17.18 (9.08-32.50) = | 3.67 (2.56-5.28) | 0.24 (0.15-0.38) | 0.88 (0.83-0.93)= |
[I2 =0.0%] | [I2 =68.2%] | [I2 =0.0%] | [I2 =63.4%] | [I2 =0.0%] | ||
EOC- advanced stage (n = 3) [uni] | 0.98 (0.94-1.00) ● | 0.76 (0.73-0.79) ● | 149.08 (47.80-464.95) | 4.17 (3.37-5.17) | 0.04 (0.01-0.13) | 0.97 (0.95-1.00) |
[I2 =49.8%] | [I2 =68.2%] | [I2 =0.0%] | [I2 =55.0%] | [I2 =28.1%] | ||
EOC- methods High concern (n = 3) [uni] | 0.90 (0.85-0.93) | 0.87 (0.83-0.90) ★● | 62.84 (3.25-112.04) | 7.29(4.33-12.26) | 0.12 (0.08-0.18) | 0.95 (0.93-0.97) |
[I2 =0.0%] | [I2 =67.5%] | [I2 =0.0%] | [I2 =58.4%] | [I2 =0.0%] | ||
EOC- methods Low concern (n = 3) [uni] | 0.89 (0.85-0.93) | 0.75 (0.72-0.78) ● | 29.57 (12.85-68.03) | 3.74 (3.29-4.25) | 0.14 (0.04-0.44) | 0.91 (0.86-0.96) |
[I2 =85.5%] | [I2 =0.0%] | [I2 =56.8%] | [I2 =0.0%] | [I2 =88.2%] | ||
EOC (LMP/BL) (n = 3) [uni] | 0.88 (0.84-0.92) | 0.77 (0.74-0.80) | 33.36 (15.02-74.06) | 4.37 (2.88-6.64) | 0.15 (0.11-0.20) | 0.92 (0.88-0.96) |
[I2 =0.0%] | [I2 =89.3%] | [I2 =66.8%] | [I2 =84.6%] | [I2 =0.0%] | ||
OC (n = 3) [uni] | 0.86 (0.82-0.89) | 0.78 (0.75-0.81) | 21. 436 (15.28-30.08) | 4.11 (3.14-5.38) | 0.19 (0.14-0.23) | 0.89 (0.87-0.92)● |
[I2 =0.0%] | [I2 =68.9%] | [I2 =0.0%] | [I2 =61.8%] | [I2 =0.0%] |