Table 1 Baseline characteristics of male Midspan cohorts at screening (1970-76) and prostate cancer outcomes. N = 12,926
| Ā | Controls | Prostate cancer cases | Gleason < 7 | Gleason = 7 | Gleason 8-10 | Unknown Gleason | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sample Size | 12,276 | Ā | 650 | Ā | 64 | Ā | 57 | Ā | 119 | Ā | 67 | Ā |
Number of Deaths%(n) | 76.4 | (9,384) | 81.1 | (527) | 51.6 | (33) | 52.6 | (30) | 73.9 | (88) | 82.1 | (55) |
Cholesterol quintiles, mmol/L,%(n) | Ā | Ā | Ā | Ā | Ā | Ā | Ā | Ā | Ā | Ā | Ā | Ā |
< 5.05 | 94.9 | (2,589) | 5.1 | (138) | 24.6 | (15) | 21.3 | (13) | 27.9 | (17) | 26.2 | (16) |
5.06 - < 5.57 | 95.3 | (2,471) | 4.7 | (121) | 17.7 | (9) | 13.7 | (7) | 37.2 | (19) | 31.4 | (16) |
5.58 - < 6.09 | 94.9 | (2,676) | 5.1 | (145) | 26.1 | (17) | 12.3 | (8) | 46.2 | (30) | 15.4 | (10) |
6.1 - < 6.69 | 94.5 | (2,161) | 5.5 | (125) | 16.9 | (12) | 18.3 | (13) | 46.5 | (33) | 18.3 | (13) |
ā„6.7 | 95.2 | (2,379) | 4.8 | (121) | 18.6 | (11) | 27.1 | (16) | 33.9 | (20) | 20.3 | (12) |
Mean Age (s.d.) | 51.1 | (7.2) | 51.7 | (6.8) | 46.9 | (6.8) | 46.7 | (6.3) | 49.2 | (6.3) | 50.7 | (6.5) |
Mean Height (s.d.) | 171.1 | (7.1) | 172.0 | (6.9) | 172.6 | (7.3) | 173.3 | (6.1) | 172.3 | (6.5) | 172.6 | (7.3) |
Mean Weight (s.d.) | 74.8 | (11.1) | 75.9 | (10.4) | 75.7 | (10.8) | 76.0 | (9.0) | 74.9 | (9.5) | 76.3 | (9.6) |
Height (cm),%(n) | Ā | Ā | Ā | Ā | Ā | Ā | Ā | Ā | Ā | Ā | Ā | Ā |
ā¤165.1 | 95.9 | (2,770) | 4.1 | (120) | 24.5 | (12) | 14.3 | (7) | 34.7 | (17) | 26.5 | (13) |
165.2-170 | 95.3 | (2,551) | 4.7 | (126) | 19.1 | (9) | 12.8 | (6) | 49.0 | (23) | 19.1 | (9) |
170.1-172.72 | 95.0 | (2,321) | 5.0 | (121) | 19.7 | (13) | 27.3 | (18) | 33.3 | (22) | 19.7 | (13) |
172.73-177.8 | 94.3 | (2,745) | 5.7 | (165) | 19.0 | (16) | 17.9 | (15) | 42.9 | (36) | 20.2 | (17) |
ā„177.9 | 94.1 | (1,887) | 5.9 | (118) | 23.0 | (14) | 18.0 | (11) | 34.4 | (21) | 24.6 | (15) |
Missing | 0.0 | (2) | 0.0 | (0) | 0.0 | (0) | 0.0 | (0) | 0.0 | (0) | 0.0 | (0) |
Mean BMI (s.d.) | 25.5 | (3.3) | 25.6 | (3.0) | 25.4 | (3.0) | 25.3 | (2.7) | 25.2 | (3.0) | 25.6 | (3.0) |
BMI (kg m -2 ),%(n) | Ā | Ā | Ā | Ā | Ā | Ā | Ā | Ā | Ā | Ā | Ā | Ā |
< 25 (Under & Desirable weight ) | 95.2 | (5,499) | 4.8 | (279) | 20.8 | (31) | 17.5 | (26) | 40.9 | (61) | 20.8 | (31) |
25 - < 30 (Overweight) | 94.7 | (5,729) | 5.3 | (320) | 21.9 | (30) | 19.7 | (27) | 34.3 | (47) | 24.1 | (33) |
ā„30 (Obese) | 95.4 | (1,046) | 4.6 | (51) | 14.3 | (3) | 19.0 | (4) | 52.4 | (11) | 14.3 | (3) |
Missing | 0.0 | (2) | 0.0 | (0) | 0.0 | (0) | 0.0 | (0) | 0.0 | (0) | 0.0 | (0) |
Smoking,%(n) | Ā | Ā | Ā | Ā | Ā | Ā | Ā | Ā | Ā | Ā | Ā | Ā |
Never smoker | 93.3 | (2,093) | 6.7 | (149) | 22.8 | (18) | 19.0 | (15) | 39.2 | (31) | 19.0 | (15) |
Smoker | 96.1 | (7,253) | 3.9 | (294) | 18.3 | (24) | 17.6 | (23) | 39.7 | (52) | 24.4 | (32) |
Ex-smoker | 93.4 | (2,929) | 6.6 | (207) | 22.7 | (22) | 19.6 | (19) | 37.1 | (36) | 20.6 | (20) |
Missing | 0.0 | (1) | 0.0 | (0) | 0.0 | (0) | 0.0 | (0) | 0.0 | (0) | 0.0 | (0) |
Social Class,%(n) | Ā | Ā | Ā | Ā | Ā | Ā | Ā | Ā | Ā | Ā | Ā | Ā |
I&II | 94.2 | (3,090) | 5.8 | (190) | 16.3 | (16) | 23.5 | (23) | 38.8 | (38) | 21.4 | (21) |
IIIN | 94.4 | (1,810) | 5.6 | (108) | 27.8 | (15) | 11.1 | (6) | 40.7 | (22) | 20.4 | (11) |
IIIM | 95.3 | (4,247) | 4.7 | (208) | 18.1 | (15) | 19.3 | (16) | 37.3 | (31) | 25.3 | (21) |
IV&V | 95.8 | (3,057) | 4.2 | (135) | 25.0 | (17) | 16.2 | (11) | 38.2 | (26) | 20.6 | (14) |
Missing | 88.9 | (72) | 11.1 | (9) | 25.0 | (1) | 25.0 | (1) | 50.0 | (2) | 0.0 | (0) |