Figure 1

Expression of Necdin is related to p53 activity in primary human fibroblasts. (A) Stimulation of IMR90 cells for 24 hrs with Nutlin-3 (2.5 μM) to induce p53 resulted in increase in Necdin protein level (B) Necdin, p21 and p53 protein expression in IMR90 cells expressing GSE22 inhibitor peptide.