miR-143 overexpression reduces the proliferative potential of DLD-1 cells. DLD-1 cells transfected with miR-143 duplex exhibit a reduced cell proliferation as measured by crystal violet growth assay. Data are shown as the mean ± S.D. of four replicates. *, p < 0.005 using a two-tailed t-test, ***, p < 0.001 using a two-tailed t-test.