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Table 2 Impact of MACC1 SNP rs1990172 on overall survival, shown for dominant, recessive, and additive genetic models of inheritance

From: A common variant of the MACC1 gene is significantly associated with overall survival in colorectal cancer patients

Genetic model

Adjustment model

HR

95%CI

P-value

Additive

Model 1

1.38

1.05-1.82

0.023

 

Model 2

1.49

1.12-1.98

0.007

Dominant

Model 1

1.59

1.05-2.40

0.028

 

Model 2

1.63

1.08-2.47

0.020

Recessive

Model 1

1.50

0.86-2.60

0.152

 

Model 2

1.82

1.04-3.18

0.036

  1. Hazard ratios (HR) and 95% confidence intervals (95% CI) were obtained from univariate Cox regression analysis (model 1) and multivariate Cox regression analysis adjusting for age and UICC stage (model 2)
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BMC Cancer

ISSN: 1471-2407

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