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Table 1 Comparison of the clinicopathological parameters of the patients according to DTC status in bone marrow after primary surgery

From: Persistent tumor cells in bone marrow of non-metastatic breast cancer patients after primary surgery are associated with inferior outcome

Variable No. of patients n = 154 Post-operatively DTC status P-values
Positive n = 23 Negative n = 131
Age     0.013
 <=55 years 78 6 (8) 72 (92)  
 >55 years 76 17 (22) 59 (78)  
Lymph node status     0.223
 pN0 110 14 (13) 96 (87)  
 pN1-2 44 9 (20) 35 (80)  
Tumor size     0.469
 pT1 105 14 (13) 91 (87)  
 pT2-4 49 9 (18) 40 (82)  
Tumor grade     0.803
 1 55 8 (14) 47 (86)  
 2 61 10 (16) 51 (84)  
 3 35 4 (11) 31 (89)  
 Unknown 3    
Estrogen receptor status     0.365
 ER positive 127 17 (13) 110 (87)  
 ER negative 25 5 (20) 20 (80)  
 Unknown 2    
Progesterone receptor status     0.105
 PgR positive 76 15 (20) 61 (80)  
 PgR negative 75 7 (9) 68 (91)  
 Unknown 3    
Histological type     0.182
 Ductal 121 15 (12) 106 (88)  
 Lobular 15 3 (20) 12 (80)  
 Mixed ductal/lobular 5 1 (20) 4 (80)  
 Other 13 4 (31) 9 (69)  
Chemotherapy     0.798
 Therapy 41 5 (12) 36 (88)  
 No therapy 113 18 (16) 95 (84)  
Endocrine therapy     0.336
 Therapy 47 9 (18) 38 (81)  
 No therapy 107 14 (13) 93 (87)  
  1. Numbers in brackets represent the number of patients in percent.