Table 3 Mortality rate and multivariable Cox proportional hazards regression model measured hazard ratio (HR) and 95% confidence interval (CI) of mortality by demographic status, co-morbidity and stage of lung cancer
From: Decreased survival among lung cancer patients with co-morbid tuberculosis and diabetes
Variables | N | Death | Person-days | Mortality rate | Rate ratio (95%CI) | HRs* (95% CI) | p-value | ||
|---|---|---|---|---|---|---|---|---|---|
Overall | 1111 | 738 | 857762 | 0.86 | |||||
Gender | |||||||||
Male | 822 | 565 | 615638 | 0.92 | 1.28 | (1.08-1.52) | 1.44 | (1.20-1.72) | <0.001 |
Female | 289 | 173 | 242124 | 0.71 | 1.00 | 1.00 | |||
Age, years | |||||||||
≤ 50 | 94 | 68 | 54514 | 1.25 | 1.47 | (1.14-1.90) | 1.29 | (0.99-1.70) | 0.064 |
51 - 60 | 155 | 98 | 114428 | 0.86 | 1.01 | (0.81-1.26) | 0.89 | (0.71-1.12) | 0.328 |
61 - 70 | 290 | 183 | 229726 | 0.80 | 0.94 | (0.79-1.12) | 1.00 | (0.83-1.20) | 0.994 |
≥ 71 | 572 | 389 | 459094 | 0.85 | 1.00 | 1.00 | |||
Comorbidity | |||||||||
Other Cancer | |||||||||
No | 1031 | 690 | 787641 | 0.88 | 1.00 | 1.00 | |||
Yes | 64 | 38 | 57496 | 0.66 | 0.75 | (0.54-1.05) | 0.77 | (0.55-1.07) | 0.124 |
Tuberculosis | |||||||||
No | 989 | 649 | 783186 | 0.83 | 1.00 | 1.00 | |||
Yes | 106 | 79 | 61951 | 1.28 | 1.54 | (1.22-1.94) | 1.30 | (1.03-1.65) | 0.030 |
COPD | |||||||||
No | 1040 | 696 | 795978 | 0.87 | 1.00 | 1.00 | |||
Yes | 55 | 32 | 49159 | 0.65 | 0.74 | (0.52-1.06) | 0.97 | (0.67-1.38) | 0.848 |
Diabetes | |||||||||
No | 967 | 633 | 768281 | 0.82 | 1.00 | 1.00 | |||
Yes | 128 | 95 | 76856 | 1.24 | 1.50 | (1.21-1.86) | 1.44 | (1.15-1.80) | 0.002 |
Hypertension | |||||||||
No | 808 | 534 | 636661 | 0.84 | 1.00 | 1.00 | |||
Yes | 287 | 194 | 208476 | 0.93 | 1.11 | (0.94-1.31) | 1.07 | (0.90-1.27) | 0.453 |
Stage | |||||||||
I | 216 | 73 | 264485 | 0.28 | 1.00 | 1.00 | |||
II | 106 | 60 | 110785 | 0.54 | 1.96 | (1.39-2.76) | 1.85 | (1.30-2.61) | 0.001 |
III | 406 | 289 | 295328 | 0.98 | 3.55 | (2.74-4.58) | 3.35 | (2.57-4.35) | <0.001 |
IV | 383 | 316 | 187164 | 1.69 | 6.12 | (4.74-7.89) | 5.63 | (4.32-7.33) | <0.001 |
p for trend | <0.001 | ||||||||