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Table 3 Mortality rate and multivariable Cox proportional hazards regression model measured hazard ratio (HR) and 95% confidence interval (CI) of mortality by demographic status, co-morbidity and stage of lung cancer

From: Decreased survival among lung cancer patients with co-morbid tuberculosis and diabetes

Variables N Death Person-days Mortality rate Rate ratio (95%CI) HRs* (95% CI) p-value
Overall 1111 738 857762 0.86      
Gender          
 Male 822 565 615638 0.92 1.28 (1.08-1.52) 1.44 (1.20-1.72) <0.001
 Female 289 173 242124 0.71 1.00   1.00   
Age, years          
 ≤ 50 94 68 54514 1.25 1.47 (1.14-1.90) 1.29 (0.99-1.70) 0.064
 51 - 60 155 98 114428 0.86 1.01 (0.81-1.26) 0.89 (0.71-1.12) 0.328
 61 - 70 290 183 229726 0.80 0.94 (0.79-1.12) 1.00 (0.83-1.20) 0.994
 ≥ 71 572 389 459094 0.85 1.00   1.00   
Comorbidity          
Other Cancer          
 No 1031 690 787641 0.88 1.00   1.00   
 Yes 64 38 57496 0.66 0.75 (0.54-1.05) 0.77 (0.55-1.07) 0.124
Tuberculosis          
 No 989 649 783186 0.83 1.00   1.00   
 Yes 106 79 61951 1.28 1.54 (1.22-1.94) 1.30 (1.03-1.65) 0.030
COPD          
 No 1040 696 795978 0.87 1.00   1.00   
 Yes 55 32 49159 0.65 0.74 (0.52-1.06) 0.97 (0.67-1.38) 0.848
Diabetes          
 No 967 633 768281 0.82 1.00   1.00   
 Yes 128 95 76856 1.24 1.50 (1.21-1.86) 1.44 (1.15-1.80) 0.002
Hypertension          
 No 808 534 636661 0.84 1.00   1.00   
 Yes 287 194 208476 0.93 1.11 (0.94-1.31) 1.07 (0.90-1.27) 0.453
Stage          
 I 216 73 264485 0.28 1.00   1.00   
 II 106 60 110785 0.54 1.96 (1.39-2.76) 1.85 (1.30-2.61) 0.001
 III 406 289 295328 0.98 3.55 (2.74-4.58) 3.35 (2.57-4.35) <0.001
 IV 383 316 187164 1.69 6.12 (4.74-7.89) 5.63 (4.32-7.33) <0.001
p for trend        <0.001  
  1. COPD: chronic obstructive pulmonary disease.
  2. * Adjusted Hazard Ratios, obtained with statistical adjustment for all the variables listed in this table.