Figure 4

IDR-E804 inhibits the growth of mouse tumors. CT-26 cells were injected subcutaneously into the right flank. After tumor formation, mice were treated with vehicle or IDR-E804 and scarified at day 20 after injection of tumor cells for the analysis. (A) Tumor growth after IDR-E804 treatment. Tumor sizes were measured daily with a caliper. (B) Changes in the body weight of mice treated with vehicle or IDR-E804. (C) Macroscopic features of tumors isolated from vehicle or IDR-E804 treated mice. (D) Tumor weight of vehicle or IDR-E804 treated mice. The results shown are the means ± S.E. of two independent experiments conducted. ^* P < 0.05, ^** P < 0.01, ^*** P < 0.001 versus vehicle treated animals.