Table 2 Associations between NOXA and MCL1 genotypes and SCCHN risk

NOXA rs9957673

 CC

216 (68.6)

246 (66.1)

1.0

118 (64.1)

1.0

128 (68.1)

1.0

 CT

95 (30.2)

115 (30.9)

1.0 (0.7-1.4)

60 (32.6)

1.1 (0.7-1.7)

55 (29.3)

1.1 (0.9-1.6)

 TT

4 (1.3)

11 (3.0)

2.3 (0.7-7.4)

6 (3.3)

1.9 (0.4-8.1)

5 (2.7)

2.0 (0.5-8.3)

P _trend =0.300

P _trend = 0.180

P _trend = 0.689

CT + TT

99 (31.4)

126 (33.9)

1.1 (0.8-1.5)

66 (35.9)

1.1 (0.7-1.7)

60 (31.9)

1.1 (0.7-1.6)

NOXA rs4558496

 TT

216 (68.6)

253 (69.1)

1.0

121 (65.8)

1.0

136 (72.3)

1.0

 TG

85 (27.5)

107 (29.3)

1.0 (0.7-1.5)

61 (33.2)

1.23 (0.8-1.9)

48 (25.5)

0.9 (0.6-1.3)

 GG

14 (4.3)

6 (1.6)

0.4 (0.2-1.1)

2 (1.1)

0.34 (0.1-1.6)

4 (2.1)

0.4 (0.1-1.4)

P _trend =0.411

P _trend = 0.913

P _trend = 0.224

 TG + GG

99 (31.4)

115 (30.9)

1.0 (0.7-1.3)

63 (34.3)

1.1 (0.7-1.7)

52 (27.7)

0.8 (0.5-1.2)

MCL1 rs9803935

 GG

95 (30.2)

127 (34.1)

1.0

65 (35.3)

1.0

62 (33.0)

1.0

 GT

157 (59.8)

169 (45.4)

0.8 (0.6-1.2)

77 (41.9)

0.8 (0.5-1.3)

92 (48.9)

0.9 (0.6-1.4)

 TT

63 (20.0)

76 (20.4)

0.9 (0.6-1.5)

42 (22.8)

1.1 (0.6-1.8)

34 (18.1)

0.9 (0.6-1.6)

P _trend =0.516

P _trend = 0.726

P _trend = 0.463

 GG + GT

252 (80.0)

296 (79.6)

1.0

142 (77.2)

1.0

154 (81.9)

1.0

 TT

63 (20.0)

76 (20.4)

1.0 (0.7-1.5)

42 (22.8)

1.2 (0.7-1.9)

34 (18.1)

1.0 (0.6-1.6)

MCL1 rs3738485

 GG

93 (29.5)

128 (34.4)

1.0

65 (35.3)

1.0

63 (33.5)

1.0

 GC

155 (49.2)

168 (45.2)

0.8 (0.6-1.2)

77 (41.9)

0.8 (0.5-1.3)

91 (47.4)

0.9 (0.6-1.3)

 CC

67 (21.3)

76 (20.4)

0.9 (0.6-1.3)

42 (22.8)

1.0 (0.6-1.7)

34 (18.1)

0.9 (0.5-1.5)

P _trend =0.298

P _trend = 0.528

P _trend = 0.271

 GG + GC

248 (78.7)

296 (79.6)

1.0

142 (77.2)

1.0

154 (81.9)

1.0

 CC

67 (21.3)

76 (20.4)

1.0 (0.7-1.4)

42 (22.8)

1.1 (0.7-1.8)

34 (18.1)

0.9 (0.6-1.5)