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Figure 5 | BMC Cancer

Figure 5

From: HOXA1 is overexpressed in oral squamous cell carcinomas and its expression is correlated with poor prognosis

Figure 5

Inhibition of HOXA1 by siRNA in SCC9 cells decreases cellular proliferation. (A) siRNA working against HOXA1 significantly decreased HOXA1 levels as revealed by representative duplex RT-PCR. (B) BrdU incorporation and Ki67 immunocytochemical expression (C) assays showed a statistically significant decrease in proliferation when HOXA1 was downregulated via siRNA (for BrdU index p < 0.01 and for Ki67 index p < 0.05). Data correspond to the mean percentage of positive cells of 3 experiments.

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