Invasion assay with double antisense microRNA (DblamiR) treated IM3 cells. U87 (A), U251 (B), and U373 (C) IM-3 cells were transfected with anti-miR-143 and anti-miR-145 (50 nM each) or with scrambled anti-miR (50 nM) as a control prior to running triplicate invasion assays. Data are represented as mean percentage of control treated cells ± SD. P: IM3: IM3 cells. C: scramble sequence miRNA control; amiR, antisense micro RNA; **, p < 0.01.