Table 5 Disease- or treatment related concomitant medication as reported by physicians
Cycle | N | Analgesics n (%) | Antiemetics n (%) | Antidiarrheals n (%) | Dexa or similar steroids n (%) | CSF n (%) | Other medications n (%) | RBC transfusions n (%) | Platelet transfusions n (%) |
|---|---|---|---|---|---|---|---|---|---|
Overall | 521 | 387 (74.3) | 435 (83.5) | 66 (12.7) | 496 (95.2) | 58 (11.1) | 292 (56.0) | 126 (24.2) | 18 ( 3.5) |
Baseline | 521 | 270 (51.8) | 182 (34.9) | 6 ( 1.2) | 244 (46.8) | 12 ( 2.3) | 187 (35.9) | 48 ( 9.2) | 5 ( 1.0) |
Cycle 1 | 516 | 265 (51.4) | 270 (52.3) | 7 ( 1.4) | 452 (87.6) | 5 ( 1.0) | 196 (38.0) | 20 ( 3.9) | 2 ( 0.4) |
Cycle 2 | 471 | 242 (51.4) | 288 (61.1) | 20 ( 4.2) | 430 (91.3) | 14 ( 3.0) | 201 (42.7) | 26 ( 5.5) | 0 ( 0.0) |
Cycle 3 | 421 | 226 (53.7) | 260 (61.8) | 16 ( 3.8) | 391 (92.9) | 14 ( 3.3) | 186 (44.2) | 29 ( 6.9) | 4 ( 1.0) |
Cycle 4 | 344 | 178 (51.7) | 215 (62.5) | 15 ( 4.4) | 327 (95.1) | 17 ( 4.9) | 155 (45.1) | 30 ( 8.7) | 3 ( 0.9) |
Cycle 5 | 278 | 142 (51.1) | 179 (64.4) | 8 ( 2.9) | 268 (96.4) | 11 ( 4.0) | 137 (49.3) | 14 ( 5.0) | 1 ( 0.4) |
Cycle 6 | 254 | 129 (50.8) | 168 (66.1) | 7 ( 2.8) | 244 (96.1) | 9 ( 3.5) | 125 (49.2) | 15 ( 5.9) | 0 ( 0.0) |
Cycle 7 | 150 | 93 (62.0) | 87 (58.0) | 4 ( 2.7) | 143 (95.3) | 4 ( 2.7) | 96 (64.0) | 7 ( 4.7) | 0 ( 0.0) |
Cycle 8 | 135 | 88 (65.2) | 64 (47.4) | 5 ( 3.7) | 131 (97.0) | 4 ( 3.0) | 87 (64.4) | 6 ( 4.4) | 1 ( 0.7) |
Cycle 9 | 110 | 75 (68.2) | 52 (47.3) | 2 ( 1.8) | 105 (95.5) | 1 ( 0.9) | 77 (70.0) | 4 ( 3.6) | 0 (0.0) |
Final | 516 | 289 (56.0) | 253 (49.0) | 21 ( 4.1) | 317 (61.4) | 25 ( 4.8) | 203 (39.3) | 60 (11.6) | 8 ( 1.6) |