|
Cycle
|
N
|
Analgesics n (%)
|
Antiemetics n (%)
|
Antidiarrheals n (%)
|
Dexa or similar steroids n (%)
|
CSF n (%)
|
Other medications n (%)
|
RBC transfusions n (%)
|
Platelet transfusions n (%)
|
|---|
|
Overall
|
521
|
387 (74.3)
|
435 (83.5)
|
66 (12.7)
|
496 (95.2)
|
58 (11.1)
|
292 (56.0)
|
126 (24.2)
|
18 ( 3.5)
|
|
Baseline
|
521
|
270 (51.8)
|
182 (34.9)
|
6 ( 1.2)
|
244 (46.8)
|
12 ( 2.3)
|
187 (35.9)
|
48 ( 9.2)
|
5 ( 1.0)
|
|
Cycle 1
|
516
|
265 (51.4)
|
270 (52.3)
|
7 ( 1.4)
|
452 (87.6)
|
5 ( 1.0)
|
196 (38.0)
|
20 ( 3.9)
|
2 ( 0.4)
|
|
Cycle 2
|
471
|
242 (51.4)
|
288 (61.1)
|
20 ( 4.2)
|
430 (91.3)
|
14 ( 3.0)
|
201 (42.7)
|
26 ( 5.5)
|
0 ( 0.0)
|
|
Cycle 3
|
421
|
226 (53.7)
|
260 (61.8)
|
16 ( 3.8)
|
391 (92.9)
|
14 ( 3.3)
|
186 (44.2)
|
29 ( 6.9)
|
4 ( 1.0)
|
|
Cycle 4
|
344
|
178 (51.7)
|
215 (62.5)
|
15 ( 4.4)
|
327 (95.1)
|
17 ( 4.9)
|
155 (45.1)
|
30 ( 8.7)
|
3 ( 0.9)
|
|
Cycle 5
|
278
|
142 (51.1)
|
179 (64.4)
|
8 ( 2.9)
|
268 (96.4)
|
11 ( 4.0)
|
137 (49.3)
|
14 ( 5.0)
|
1 ( 0.4)
|
|
Cycle 6
|
254
|
129 (50.8)
|
168 (66.1)
|
7 ( 2.8)
|
244 (96.1)
|
9 ( 3.5)
|
125 (49.2)
|
15 ( 5.9)
|
0 ( 0.0)
|
|
Cycle 7
|
150
|
93 (62.0)
|
87 (58.0)
|
4 ( 2.7)
|
143 (95.3)
|
4 ( 2.7)
|
96 (64.0)
|
7 ( 4.7)
|
0 ( 0.0)
|
|
Cycle 8
|
135
|
88 (65.2)
|
64 (47.4)
|
5 ( 3.7)
|
131 (97.0)
|
4 ( 3.0)
|
87 (64.4)
|
6 ( 4.4)
|
1 ( 0.7)
|
|
Cycle 9
|
110
|
75 (68.2)
|
52 (47.3)
|
2 ( 1.8)
|
105 (95.5)
|
1 ( 0.9)
|
77 (70.0)
|
4 ( 3.6)
|
0 (0.0)
|
|
Final
|
516
|
289 (56.0)
|
253 (49.0)
|
21 ( 4.1)
|
317 (61.4)
|
25 ( 4.8)
|
203 (39.3)
|
60 (11.6)
|
8 ( 1.6)
|
-
CSF colony stimulating factors, Dexa dexamethasone, N = number of patients per cycle, RBC red blood cells
