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Table 2 Correlation between pMEK5 expression and clinicopathologic characteristics

From: Expression of the phosphorylated MEK5 protein is associated with TNM staging of colorectal cancer

Variable Cases pMEK5 protein Pvalue
   Normal expression Overexpression  
Sex     0.055
   Female 158 79(50.0%) 79(50.0%)  
   Male 177 70(39.5%) 107(60.5%)  
Age at surgery, years     0.835
   < 65 189 85(45.0%) 104(55.0%)  
   ≥ 65 146 64(43.8%) 82(56.2%)  
Tumour location     0.440
   Right colon 57 21(36.8%) 36(63.2%)  
   Left colon 99 45(44.5%) 54(54.5%)  
   Rectum 179 83(46.4%) 96(53.6%)  
pT (invasion depth)     0.001
   T1+ T2 62 39(62.9%) 23(37.1%)  
   T3+ T4 273 110(40.3%) 163(59.7%)  
pN (lymph node metastasis)     < 0.001
   N0 203 113(55.7%) 90(44.3%)  
   N1-N2 132 36(27.3%) 96(72.7%)  
pM (distant metastasis)     < 0.001
   M0 305 146(47.9%) 159(52.1%)  
   M1 30 3(10.0%) 27(90.0%)  
TNM stage     < 0.001
   I 49 35(71.4%) 14(28.6%)  
   II 145 78(53.8%) 67(46.2%)  
   III 111 33(29.7%) 78(70.3%)  
   IV 30 3(10.0%) 27(90.0%)  
Differentiation grade     0.074
   Well 29 17(58.6%) 12(41.4%)  
   Moderate 278 124(44.6%) 154(55.4%)  
   Poorly 28 8(28.6%) 20(71.4%)  
Preoperative CEA level     < 0.001
   < 5 ng/ml 190 102(53.7%) 88(46.3%)  
   ≥ 5 ng/ml 145 47(32.4%) 98(67.6%)  
Preoperative CA19-9 level     0.251
   < 60 U/ml 296 135(45.6%) 161(54.4%)  
   ≥ 60 U/ml 39 14(35.9%) 25(64.1%)