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Table 4 Analysis of polymorphisms and lung cancer risk in CAPUA study population

From: Genetic polymorphisms in MMP 2, 9 and 3genes modify lung cancer risk and survival

MMPs Genotype Cases
n (%)
Controls
n (%)
ORa [95% CI] P P trend
MMP9 C/C 581 (76.2) 483 (74.4) 1.00    
  C/T 174 (22.8) 148 (22.8) 0.96 0.69-1.35 0.830  
  T/T 7 (0.9) 18 (2.8) 0.23 0.06-0.85 0.027 0.202
MMP2 C/C 596 (73.0) 465 (76.2) 1.00    
  C/T 206 (25.2) 125 (20.5) 1.18 0.83-1.67 0.359  
  T/T 14 (1.7) 20 (3.3) 0.86 0.35-2.13 0.749 0.601
MMP3 6A/6A 185 (25.8) 139 (26.0) 1.00    
  6A/5A 367 (51.3) 276 (51.7) 1.19 0.83-1.72 0.339  
  5A/5A 164 (22.9) 119 (22.3) 1.17 0.76-1.81 0.483 0.331
  1. aAdjusted by age, gender, pack-years, family history of cancer, occupation (list A), alcohol consumption (gr), and calories