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Table 2 Characteristics of lung cancer cases and controls patients of CAPUA study

From: Genetic polymorphisms in MMP 2, 9 and 3genes modify lung cancer risk and survival

Variable Cases (n = 879)
n (%)
Controls (n = 803)
n (%)
P a
Gender    
   Male 785 (89.3) 688 (85.7)  
   Female 94 (10.7) 115 (14.3) 0.024
Age (yrs), mean (SD) 66.1 (10.6) 64.4 (11.2) 0.002
Smoking Status    
   Never 53 (6.1) 231 (29.1)  
   Ever 821 (93.9) 563 (70.9) 0.000
Former 369 (42.3) 337 (43.0)  
Current 449 (51.5) 215 (27.5) 0.000
Pack-years b, mean (SD) 62.2 (36.2) 36.3 (30.8) 0.000
Family history of cancer    
   No 486 (58.3) 473 (60.3)  
   Yes 347 (41.7) 311 (39.7) 0.416
Lung cancer 91 (10.9) 52 (6.6)  
Other cancers 256 (30.7) 259 (33.0) 0.009
Histological types    
   Squamous cell carcinoma 358 (40.7)   
   Adenocarcinoma 264 (30.0)   
   Small cell carcinoma 150 (17.1)   
   Non-differentiated 54 (6.1)   
   Large cell carcinoma 24 (2.7)   
   Others 15 (1.7)   
   Clinical diagnosis 6 (0.7)   
   Missing 8 (0.9)   
Clinical stages
NSCLC
   
   I 186 (25.9)   
   II 58 (8.1)   
   III 245 (34.1)   
   IV 229 (31.9)   
SCLC    
   LS (Limited stage) 78 (52.3)   
   ES (Extend stage) 71 (47.7)   
Calories, mean (SD) 2405.6 (845.4) 2276.9 (700.4) 0.045
Alcohol consumption (gr), mean (SD) 26.4 (39.7) 22.2 (35.5) 0.033
Occupation (list A)    
   No 703 (80.7) 677 (87.1)  
   Yes 168 (19.3) 100 (12.9) 0.000
  1. a Two-sided χ2 test and Mann-Whitney where appropriate
  2. b Pack-years for ever smokers