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Table 1 Clinical characteristics of 9 patients with esthesioneuroblastoma

From: Esthesioneuroblastoma in pediatric and adolescent age. A report from the TREP project in cooperation with the Italian Neuroblastoma and Soft Tissue Sarcoma Committees

Pt. Sex/age at dgn (years) Symptoms Primary site Tumor extension Tumor size TNM Kadish
stage
1 M/4 Seizures Rhinopharynx Intracranial, bone erosion, cervical lymph nodes > 5 cm T2b, N1, M0 C
2 M/2 Exophthalmos Nasal cavity, rhinopharynx and ethmoid sinuses Orbital cavity, submandibular lymph node, bone erosion > 5 cm T2b, N1, M0 C
3 F/16 Recurrent epistaxis Paranasal sinuses - > 5 cm T1b, N0, M0 B
4 M/10 None Nasal cavity, rhinopharynx and maxillary sinuses Bone erosion < 5 cm T2a, N0, M0 B
5 M/1 Recurrent epistaxis Nasal cavity, ethmoid sinuses Intracranial, bone erosion > 5 cm T2b, N0, M0 C
6 M/11 Nasal obstruction Nasal cavity, maxillary and ethmoid sinuses - > 5 cm T2b, N0, M0 B
7 M/5 Cranial nerve palsy Nasal cavity pterygomandibular, infratemporal fossae Intracranial, orbital cavity, bone erosion > 5 cm T2b, N0, M0 C
8 F/18 Proptosis Nasal cavity Intracranial, orbital cavity, retromandibular and laterocervical lymph nodes, bone erosion > 5 cm T2b, N1, M0 C
9 F/17 Headache Maxillary and ethmoid sinuses Orbital cavity, bone erosion > 5 cm T2b, N0, M0 C
  1. Pt: patient; dgn: diagnosis; M: male; F: female.