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Table 1 Clinical characteristics of 9 patients with esthesioneuroblastoma

From: Esthesioneuroblastoma in pediatric and adolescent age. A report from the TREP project in cooperation with the Italian Neuroblastoma and Soft Tissue Sarcoma Committees

Pt.

Sex/age at dgn (years)

Symptoms

Primary site

Tumor extension

Tumor size

TNM

Kadish

stage

1

M/4

Seizures

Rhinopharynx

Intracranial, bone erosion, cervical lymph nodes

> 5 cm

T2b, N1, M0

C

2

M/2

Exophthalmos

Nasal cavity, rhinopharynx and ethmoid sinuses

Orbital cavity, submandibular lymph node, bone erosion

> 5 cm

T2b, N1, M0

C

3

F/16

Recurrent epistaxis

Paranasal sinuses

-

> 5 cm

T1b, N0, M0

B

4

M/10

None

Nasal cavity, rhinopharynx and maxillary sinuses

Bone erosion

< 5 cm

T2a, N0, M0

B

5

M/1

Recurrent epistaxis

Nasal cavity, ethmoid sinuses

Intracranial, bone erosion

> 5 cm

T2b, N0, M0

C

6

M/11

Nasal obstruction

Nasal cavity, maxillary and ethmoid sinuses

-

> 5 cm

T2b, N0, M0

B

7

M/5

Cranial nerve palsy

Nasal cavity pterygomandibular, infratemporal fossae

Intracranial, orbital cavity, bone erosion

> 5 cm

T2b, N0, M0

C

8

F/18

Proptosis

Nasal cavity

Intracranial, orbital cavity, retromandibular and laterocervical lymph nodes, bone erosion

> 5 cm

T2b, N1, M0

C

9

F/17

Headache

Maxillary and ethmoid sinuses

Orbital cavity, bone erosion

> 5 cm

T2b, N0, M0

C

  1. Pt: patient; dgn: diagnosis; M: male; F: female.