Table 4 KRAS genotype frequencies and HR status and HER2 status according to HRT stratification
Study population | Genotype | Frequency | p | Frequency p | p | ||
|---|---|---|---|---|---|---|---|
| Â | Â | N(%) | value | N(%) | value | ||
| Â | Â | HR+ | HR- | Â | HER2+ | HER2- | Â |
All | wild(TT) | 363(82.9) | 69(83.1) | 0.955 | 49(77.8) | 372(84.0) | 0.218 |
| Â | variable(TG/GG) | 75(17.1) | 14(16.9) | Â | 14(22.2) | 71(16.0) | Â |
Nonusers: HRT < 1 year | wild(TT) variable(TG/GG) | 250(81.7) 56(18.3) | 52(85.2) 9(14.8) | 0.508 | 41(83.7) 8(16.3) | 255(82.8) 53(17.2) | 0.879 |
Users: HRT 1 years | wild(TT) | 113(85.6) | 17(77.3) | 0.318 | 8(57.1) | 117(86.7) | 0.004 |
| Â | variable(TG/GG) | 19(14.4) | 5(22.7) | Â | 6(42.9) | 18(13.3) | Â |