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Table 1 Association between GPR39 expression and clinical characteristics of ESCC patients (n = 207)

From: Overexpression of GPR39 contributes to malignant development of human esophageal squamous cell carcinoma

Clinicopathologic characteristics GPR39 expression no. (%) P
  Overexpression Low expression  
Age (y)    
   ≤60 69 (59.5) 47 (40.5) 0.735
   >60 52 (57.1) 39 (42.9)  
Sex    
   Male 68 (57.6) 50 (42.4) 0.887
   Female 53 (59.6) 36 (40.4)  
Tumor location    
   Upper 22 (53.7) 19 (46.3) 0.762
   Middle 82 (59.4) 56 (40.6)  
   Lower 16 (61.5) 10 (38.5)  
Tumor cell differentiation    
   Well 15 (53.6) 13 (46.4) 0.846
   Moderate 76 (58.9) 53 (41.1)  
   Poor 30 (60.0) 20 (40.0)  
Tumor invasion (T)    
   T1 2 (25) 6 (75) 0.085
   T2 44 (65.7) 23 (34.3)  
   T3 75 (57.3) 56 (42.7)  
   T4 1 (100) 0 (0)  
Lymph node metastasis (N)    
   N0 59 (50.4) 58 (49.8) 0.008*
   N1 62 (68.9) 28 (31.1)  
TNM stage    
   I 1 (14.3) 6 (85.7) 0.004*
   IIa 57 (52.3) 52 (47.7)  
   IIb 15 (75.0) 5 (25.0)  
   III-IV 48 (67.6) 23 (32.4)  
  1. * Statistically significant (P < 0.05)