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Table 3 Relative risk of second primary cancer by type of first primary cancer and age group at first diagnosis, Queensland, 1982-2006

From: The relative risk of second primary cancers in Queensland, Australia: a retrospective cohort study

 

Age group at first diagnosis

 

15-49 years

50-64 years

65 years and over

First primary cancer

Obs.

SIR

(95% CI)

Obs.

SIR

(95% CI)

Obs.

SIR

(95% CI)

   Head and neck

223

2.07

(1.80-2.36)

884

2.20

(2.06-2.35)

882

1.77

(1.65-1.89)

   Oesophagus

6

4.00

(1.47-8.70)

39

1.70

(1.21-2.32)

60

1.16

(0.88-1.49)

   Stomach

17

1.59

(0.93-2.55)

60

1.04

(0.79-1.34)

129

0.91

(0.76-1.08)

   Colorectal

188

1.58

(1.36-1.82)

994

1.15

(1.08-1.22)

1,864

1.03

(0.99-1.08)

   Pancreas

--

--

26

1.60

(1.05-2.35)

23

0.61

(0.39-0.92)

   Lung

52

2.46

(1.84-3.23)

270

1.55

(1.37-1.74)

407

1.24

(1.12-1.36)

   Melanoma

1,121

2.05

(1.94-2.18)

1,755

1.80

(1.72-1.89)

2,216

1.74

(1.67-1.81)

   Breast - female

689

1.86

(1.72-2.00)

1,047

1.29

(1.21-1.37)

1,226

1.15

(1.08-1.21)

   Cervix

129

1.33

(1.11-1.57)

94

1.49

(1.21-1.83)

77

1.27

(1.01-1.59)

   Uterus

47

1.63

(1.20-2.17)

164

1.07

(0.91-1.25)

198

1.16

(1.00-1.33)

   Ovary

33

1.25

(0.86-1.76)

64

1.12

(0.87-1.44)

67

1.06

(0.82-1.34)

   Prostate

7

0.81

(0.32-1.66)

554

0.87

(0.80-0.95)

2,445

0.82

(0.79-0.85)

   Kidney

52

1.63

(1.22-2.14)

230

1.59

(1.39-1.81)

373

1.57

(1.42-1.74)

   Bladder

81

2.02

(1.60-2.51)

465

1.63

(1.49-1.79)

1,134

1.70

(1.60-1.80)

   Brain & CNS

27

1.64

(1.08-2.39)

15

0.94

(0.52-1.55)

8

0.48

(0.21-0.95)

   Thyroid

65

1.22

(0.94-1.55)

84

1.39

(1.11-1.72)

66

1.37

(1.06-1.74)

   Non-Hodgkin lymphoma

81

1.60

(1.27-1.99)

261

1.57

(1.39-1.77)

347

1.23

(1.10-1.36)

   Lymphoid leukaemia

27

2.68

(1.77-3.90)

131

1.69

(1.42-2.01)

264

1.57

(1.39-1.77)

   Myeloid leukaemia

22

2.23

(1.40-3.38)

33

1.39

(0.96-1.95)

70

1.35

(1.05-1.70)

   Myeloma/PCT

8

1.40

(0.61-2.77)

47

1.35

(0.99-1.79)

79

0.89

(0.70-1.10)

   Other

273

1.69

(1.49-1.90)

472

1.43

(1.30-1.56)

808

1.20

(1.12-1.29)

   All cancers combined

3,150

1.84

(1.77-1.90)

7,687

1.39

(1.36-1.42)

12,743

1.23

(1.20-1.25)

  1. Obs. = Observed number of second primary cancers; SIR = standardised incidence ratio; CI = confidence interval; CNS = central nervous system; PCT = plasma cell tumours. SIRs shown in normal bold font indicate significantly increased risk; SIRs shown in bold italics indicate significantly decreased risk. SIRs for pancreatic cancer for the age groups 15-49 years and 50-64 years have been combined due to less than 5 observed cases aged 15-49 years.