Figure 1
From: Involvement of promoter methylation in the regulation of Pregnane X receptor in colon cancer cells
Location of the CpG sequences examined. CpG sites (vertical bars), CpG islands identified by CpG island searcher (horizontal thick lines) and transcription start sites within the 5' prime region (curved arrows) are shown in the (a), PXR; (b), CYP3A4; (c), VDR; and (d), PRMT1 genes. The segments indicated by double-pointed arrows were examined for DNA methylation by bisulfite direct sequencing.