Figure 2
From: The level of claudin-7 is reduced as an early event in colorectal carcinogenesis
Claudin-7 mRNA levels in healthy individuals, individuals with dysplasia and individuals with carcinomas as determined by real-time RT-PCR. Samples from healthy individuals (cross), normal (open circle) and affected tissue (filled circle) from individuals with mild/moderate dysplasia, normal (open square) and affected tissue (filled square) from individuals with severe dysplasia, normal adjacent (open triangle), normal distant (open triangle) and carcinomatous tissue (filled diamond) from colorectal cancer patients were analysed for claudin-7 mRNA levels relative to the β-actin mRNA levels. The horizontal line represents the mean values. The p-value indicated with a ¤ is calculated using Kruskal Wallis and Dunn's Multiple Comparison test and p-values marked with a * are calculated using Paired Student's t-test.