From: Tyrosine kinase chromosomal translocations mediate distinct and overlapping gene regulation events
Microarray Analysis | ||
---|---|---|
Genes Regulated by TEL-JAK2 | ||
Fold-Change | Gene Name | |
Induced Genes | 3.90 | 0-6-methylguanine-DNA methyltransferase (Mgmt) |
3.20 | Serum deprivation response (Sdpr) | |
3.18 | Growth arrest specific 5 (Gas5) | |
3.13 | Immediate early response 2 (Ier2) | |
2.74 | Cbp/p300 interacting transactivator 2 (Cited2) | |
2.69 | E2f transcription factor 6 (E2f6) | |
2.38 | Pannexin 1 (Panx1) | |
2.17 | Myosin VIIa (Myo7a) | |
2.12 | Tnf receptor-associate factor 5 (Traf5) | |
2.12 | Cyclin-dependent kinase inhibitor 2a (Cdkn2a) | |
2.00 | Rab33b, member of Ras oncogene family (Rab33b) | |
Suppressed Genes | 6.81 | Chemokine (C-C) receptor 1 (Ccr1) |
3.30 | Apoptosis inhibitory protein 5 (Api5) | |
2.98 | Bcl2 adenovirus E1b 19 kDa interacting protein 3-like (Bnip3) | |
2.85 | Runt-related transcription factor 1 (Runx1) | |
2.68 | Lim only 4 (Lmo4) | |
2.61 | Chemokine (CXC motif) ligand 13 (Cxcl13) | |
2.47 | Axin1 (Axin1) | |
2.17 | Rho family GTPase RhoA (RhoA) | |
2.12 | Chemokine (C-C motif) receptor 1 (Ccr1) |