Data output from transcriptomic analyses and outline of experimental design. Figure 4A: Global transcriptomic response in each array experiment displaying the number of up and down regulated genes in each array comparison (upper panel). 4B: The unique cell lines from which RNA was extracted for microarray analysis. RNA was extracted from each of the 3 experimental cell lines, control 'non target' cells and knockdown 63 and 65, in duplicate, from cells in resting and stimulated (10 μM LPA) states(center panel). 4C: Microarray data comparisons to determine (1) NET1 dependent transcription, (2) LPA dependent transcriptionand (3) NET1 mediated LPA dependent genetic events (lower panel).