Table 3 Distribution of gene polymorphisms
From: Pharmacogenetic profiling and cetuximab outcome in patients with advanced colorectal cancer
Gene | Genotype | N | |
|---|---|---|---|
EGFR | CA-repeats (intron 1) | Sum of CA ≤ 35 | 33 |
Sum of CA > 35 | 23 | ||
-216G>T | GG | 16 | |
GT | 29 | ||
TT | 11 | ||
-191C>A | CC | 45 | |
CA | 11 | ||
AA | 1 | ||
R497K | RR | 29 | |
RK | 18 | ||
KK | 8 | ||
EGF | 61A>G | AA | 25 |
AG | 21 | ||
GG | 9 | ||
CCND1 | A870G | AA | 9 |
AG | 35 | ||
GG | 12 | ||
FCGR2A | R131H | RR | 20 |
RH | 29 | ||
HH | 7 | ||
FCGR3A | F158V | FF | 30 |
FV | 20 | ||
VV | 6 |