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Table 5 Mutations and clinical findings

From: Hepatitis B virus core promoter mutations G1613A and C1653T are significantly associated with hepatocellular carcinoma in genotype C HBV-infected patients

HCC group 2 (n = 40)     
Mutation (1613/1653) -/- +/- -/+ +/+
n 14 6 6 14
HBeAg (positive) 40% 60% 50% 67%
Sex (Male) 79% 83% 83% 71%
Patient age 54.6 ± 14.3- 43.3 ± 6.7 57.8 ± 18.3 57.8 ± 9.5
Non-HCC group 2 (n = 52)     
Mutation (1613/1653) -/- +/- -/+ +/+
n 43 3 3 3
HBeAg (positive) 78% 50% 33% 100%
Sex (Male) 81% 100% 67% 100%
Patient age 37.8 ± 11.0 32.0 ± 17.3 48.7 ± 7.0 30.7 ± 10.2