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Table 4 Correlation between metabolic, and histopathologic response.

From: Early metabolic response using FDG PET/CT and molecular phenotypes of breast cancer treated with neoadjuvant chemotherapy

Response Histopathologic responders * Histopathologic
non-responders
P-value
Metabolic responders    
   Responders 12 (32.4%) 25 (67.6%) 0.002
   Non-responders 2 (4.9%) 39 (95.1%)  
  For histopathologic responders For histopathologic nonresponder  
   Sensitivity 85.7% (12/14) 60.9% (39/64)  
   Specificity 60.9% (39/64) 85.7% (12/14)  
   Positive predictive value 32.4% (12/37) 95.1% (39/41)  
   Negative predictive value 95.1% (39/41) 32.4% (12/37)  
  1. * Pathologic complete response or minimal residual disease were regarded as histopathologic responders, Gross residual disease were regarded as histopathologic non-responders.
  2. P-value based on the Fisher's exact test