Cancer associated epigenetic transitions identified by genome-wide histone methylation binding profiles in human colorectal cancer samples and paired normal mucosa

Table 2 Comparisons between H3K27me3 target genes in colon tissue samples and CRC cell lines.

The different gene categories considered (in bold) consisted of the genes marked by H3K27me3 in normal or tumor samples from patient 1 or patient 2, genes bound by H3K27me3 in HT29 CRC cell line and genes bound by SUZ12 in SW480 CRC cell line. Only genes were both H3K27me3 data in tissues samples and HT29 cell line and SUZ12 data in SW480 cell line were available were considered (total = 7393), which was limited by the coverage of the arrays used. The numbers in the diagonal of the table (in bold) indicate all genes included in each category, while the remaining numbers indicate the overlaps between each pair of categories considered in each case.

ISSN: 1471-2407