Chromosomal aberrations and aneuploidy in oral potentially malignant lesions: distinctive features for tongue

BMC Cancer

Table 3 Distribution of patients with OPMLs in the tongue (T patients) or in all the other oral mucosal subsites (O patients) or in Buccal Mucosa (BM patients) with respect to DNA diploid or aneuploid status and to dysplastic or non-dysplastic status.

		Dysplastic + Non-dysplastic OPMLs
	O patients vs. T patients	(OR = 5.2; p = 0.003)*
		T patients vs. BM patients	(OR = 5.9; p = 0.002)^§
	O patients	T patients	BM patients
DNA diploid	71	10	54
DNA aneuploid	15 (17%)	11 (52%)	10 (16%)
Total	86	21	64
		Non-dysplastic OPMLs
	O patients vs. T patients	(OR = 3.6; p = 0.07)
		T patients vs. BM patients	(OR = 3.6; p = 0.069)
	O patients	T patients	BM patients
DNA diploid	65	9	48
DNA aneuploid	12 (16%)	6 (40%)	9 (16%)
Total	77	15	57
		Dysplastic OPMLs
	O patients vs. T patients	(OR = 10; p = 0.12)
		T patients vs. BM patients	(OR = 36; p = 0.029)
	O patients	T patients	BM patients
DNA diploid	6	1	6
DNA aneuploid	3 (33%)	5 (83%)	1 (14%)
Total	9	6	7

*Once stratified for presence/absence of dysplasia in the corresponding OPMLs, OR_M-H = 4.5 (p = 0.005).
^§ Once stratified for presence/absence of dysplasia in the corresponding OPMLs, OR_M-H = 5.2 (p = 0.003).

ISSN: 1471-2407