Table 2 Test characteristics of single and double FIT sampling for detection of screen relevant neoplasia

Cut-off 50

47, 6%

88, 2%

54, 0%

83, 0%

43, 5%

93, 2%

52, 4%

88, 8%

N

59/124

844/957

67/124

794/957

54/124

892/957

65/124

850/957

(CI)

(39-57)

(86-90)

(45-63)

(80-85)

(35-53)

(91-95)

(43-61)

(87-91)

Cut-off 75

46, 0%

90, 5%

52, 4%

87, 4%

41, 1%

94, 4%

46, 8%

91, 3%

N

57/124

866/957

65/124

836/957

51/124

903/957

58/124

874/957

(CI)

(37-55)

(88-92)

(43-61)

(85-89)

(32-50)

(93-96)

(38-56)

(89-93)

Cut-off 100

45, 2%

92, 5%

51, 6%

89, 8%

39, 5%

95, 5%

44, 4%

92, 8%

N

56/124

885/957

64/124

859/957

49/124

914/957

55/124

888/957

(CI)

(36-54)

(91-94)

(42-61)

(88-92)

(31-49)

(94-9s7)

(35-54)

(91-94)

Cut-off 150

42, 7%

94, 6%

47, 6%

92, 2%

35, 5%

96, 8%

38, 7%

94, 1%

N

53/124

905/957

59/124

882/957

44/124

926/957

48/124

901/957

(CI)

(34-52)

(93-96)

(39-57)

(89-93)

(27-45)

(95-98)

(30-48)

(92-96)

Cut-off 200

37, 9%

95, 1%

41, 9%

93, 2%

34, 7%

97, 5%

37, 1%

96, 1%

N

47/124

910/957

52/124

892/957

43/124

933/957

46/124

920/957

(CI)

(29-47)

(94-96)

(39-57)

(91-95)

(26-44)

(96-98)

(29-46)

(95-97)