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Table 1 Histological evaluation of Medium- and RSV-injected tumors

From: Oncolytic targeting of androgen-sensitive prostate tumor by the respiratory syncytial virus (RSV): consequences of deficient interferon-dependent antiviral defense

Slide ID Injection Invasion m/hpf Necrosis Compression Min. NV
1 Medium 4 2 2 2 0 5
2 Medium 4 11 1 1 0 3
3 Medium 5 22 2 2 0 2
4 RSV 0 0 5 0 4 2
5 RSV 0 0 5 0 3 2
6 RSV 0 0 5 0 3 0
  1. Histological evaluations of RSV-injected versus medium-injected tumors (3 tumor specimens in each group) are presented. Tumor sections were stained with hematoxylin and eosin. For each tumor sample, pathologic changes were graded by a blinded, board certified veterinary pathologist (GBH) as 0 = normal, 1 = minimal, 2 = mild, 3 = moderate, 4 = moderately severe, 5 = severe. Grading criteria were based on invasion of adjacent normal tissue, necrosis, mitotic figures per 20X high power field (m/hpf*), compression of the surrounding tissue, mineralization (min§) and neovascularization (NVII).