Early mortality and overall survival in oncology phase I trial participants: can we improve patient selection?

BMC Cancer

Table 2 90 day mortality, overall survival and response data of entire cohort

Outcome		Number	%	Median (days)	95% CI (days)
90 day mortality	Alive ≥ 90 days	200	86
	Alive < 90 days	33	14
Overall survival				320	270-365
Response by RECIST	Partial Response	17/196	9
	Stable Disease	92/196	47
	Progressive Disease	87/196	44
Stable disease duration	0-3 months	20/86	23
	3-6 months	46/86	54
	> 6 months	20/86	23
Stable disease duration	1-2 cycles	13/90	15
	3-4 cycles	23/90	26
	5-6 cycles	29/90	32
	> 6 cycles	25/90	27

Abbreviations: RECIST = Response Evaluation Criteria In Solid Tumors; CI = confidence interval

ISSN: 1471-2407