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Table 1 Distribution of CCND1 and ID1 gene expression according to clinico- pathological parameters in breast cancer patients

From: Cyclin D1, Id1 and EMT in breast cancer

  CCND1   ID1  
Variable 1
N = 277
2
N = 276
3
N = 277
4
N = 277
  1
N = 277
2
N = 276
3
N = 277
4
N = 277
 
ERα positive (%)
P- value
(R-value)
     < 0.001†
(0.306)
     0.529†
(0.021)
< 10 118 49 44 28   61 66 52 60  
≥ 10 117 177 195 211   172 170 182 176  
Missing cases: 168           
NHG
P- value
(R-value)
     0.002
(-0.098)
     < 0.001
(-0.199)
I 27 48 60 32   22 41 44 60  
II 72 79 86 93   77 78 87 88  
III 96 73 53 65   90 84 62 51  
Missing cases: 323           
Lymph node status
P- value
(R-value)
     0.360†
(0.030)
     0.078†
(-0.058)
N = 0 192 198 200 190   190 190 197 203  
N > 0 41 30 39 47   43 48 33 33  
Missing cases: 170           
Tumour size, mm
P- value
(R-value)
     0.415†
(-0.032)
     0.005†
(-0.109)
≤ 20 71 90 97 80   63 91 89 95  
> 20 90 75 73 86   95 83 69 77  
Missing cases: 445           
  1. * Correlations were calculated using Spearman's ρ unless otherwise specified
  2. † Wilcoxon/Mann-Whitney test (two-sided)
  3. ER, Oestrogen receptor; NHG, Nottingham Histologic Grade.