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Table 4 Multivariate Analysis of Overall Survival, Cox Model (n = 130)

From: Brain metastases from breast cancer: prognostic significance of HER-2 overexpression, effect of trastuzumab and cause of death

Covariate

Comparison

Hazard Ratio for death

[CI 95%]

P

N = 127

HER-2 positive patients treated with trastuzumab

Yes vs No

0.49 [0.29;0.83]

0.00810

KPS

≥ 70 vs. < 70

0.56 [0.37; 0.85]

0.00578

  1. Abbreviations: KPS: Karnofsky performance status