Table 3 Relationships between CAIX and HIF-1α & clinicopathological variables
From: Overexpression of carbonic anhydrase and HIF-1α in Wilms tumours
Characteristic | No | No (%) stained for CAIX | p-value | No (%) stained for HIF-1α | p-value |
|---|---|---|---|---|---|
Relapse/metastases | |||||
Present | 8 | 4 | > 0.99 | 6 | 0.49 |
Absent | 62 | 40 (65%) | 59 (95%) | ||
Chemotherapy status | |||||
Pre-CT | 22 | 16 (73%) | 0.47 | 20 (91%) | 0.29 |
Post-CT | 40 | 24 (60%) | 39 (98%) | ||
Stage Post-CT | |||||
1 | 14 | 9 (64%) | 0.85 | 14 (100%) | † |
2 | 13 | 7 (54%) | 13 (100%) | ||
3/4/5 | 13 | 8 (62%) | 12 (92%) | ||
Risk group Post-CT | |||||
High-risk | 5 | 2 | 0.37 | 5 | > 0.99 |
Low/Intermediate risk | 35 | 22 (63%) | 34 (97%) | ||
Histological type Post-CT | |||||
Blastemal | 8 | 3 | † | 8 | † |
Epithelial/Stromal | 10 | 9 (90%) | 10 (100%) | ||
Mixed | 16 | 8 (50%) | 15 (94%) | ||
Regressive | 6 | 4 | 6 | ||
*Size (cm) Post-CT | > 0.99 | 0.45 | |||
≤9 | 22 | 13 (59%) | 22 (100%) | ||
> 9 | 18 | 11 (61%) | 17 (94%) | ||
**Weight (g) Post-CT | |||||
≤299 | 20 | 7 (35%) | 0.057 | 17 (85%) | > 0.99 |
> 299 | 20 | 14 (70%) | 17 (85%) |