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Table 2 HIF-1α, CA IX, GLUT1 and VEGF expression in pre-chemotherapy WTs

From: Overexpression of carbonic anhydrase and HIF-1α in Wilms tumours

Marker Tumours +ve (%) Level of expression (median) Pattern of co-expression
   CA IX 56 0-60 (5) + + + + - - - - + + - - + - +
   HIF-1α 94 0-80 (40) + + + - + - - - + - + + - + -
   GLUT1 100 30-80 (60) + + - + + + - - - - + - + - -
   VEGF 94 5-90 (10) + - + + + + + - - - - - - + +
Co-expressiona    7 1 0 1 5 0 0 0 0 0 0 0 0 0 0
Co-localizationb    6 1 0 0 4 0 0 0 0 0 1 0 0 0 0
  1. Table shows expression in pre-chemotherapy WT samples that were CA IX positive (n = 14).
  2. a number of positive cases showing specific staining of all four markers (+ or - sign in each line indicates positivity and negativity in respective staining in the same tumour)
  3. b number of positive cases showing specific staining of all four markers (+ or - sign in each line indicates positivity and negativity in respective staining in the same area of the same tumour)