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Table 1 Analysis of Mammary Gland Growth

From: A moderate elevation of circulating levels of IGF-I does not alter ErbB2 induced mammary tumorigenesis

Group Wild Type (control) Transgenic (TTR-IGF-I)
Average. % Fat Pad Filled 4 wks 26% 28%
Average. % Fat Pad Filled 6 wks 80% 87%
Average. % Fat Pad Filled 9 wks 82% 82%
  1. There was no difference in mammary gland development compared to age-matched wild types at 4, 6 and 9 weeks of age as determined by percent of the mammary fat pad filled with the ductal tree. N = 20 for WT and TG at 4 wks of age; N = 4 for WT and 7 for TG at 6 wks of age; N = 7 for WT and N = 8 for TG at 9 wks of age. WT = wild type and TG = TTR-IGF-I