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Table 3 Expression levels of plasma miRNAs in healthy smokers, patients with benign SPNs, and patients with malignant SPNs

From: Diagnosis of lung cancer in individuals with solitary pulmonary nodules by plasma microRNA biomarkers

 

Healthy smokers

Patients with benign SPNs

Patients with malignant SPNs

MiRNAs

Expression levels of each miRNA, Median (SD)

miR-375

1.698 (0.1996)

1.611 (0.3110)

1.735 (0.3027)

miR-126

7.531 (1.050)

6.133 (0.6545)

6.292 (0.6652)

miR-21

0.639 (0.4707)

4.401 (1.2820)â–¡

5.47 (1.3450)*

miR-210

1.126 (0.2952)

1.769 (0.4759)â–¡

2.252 (0.6174)*

miR-486-5p

8.088 (1.3610)

5.668 (1.641)â–¡

4.019 (1.6290)*

  1. SPNs, solitary pulmonary nodules; SD, standard deviation. *, statistical significance between patients with malignant SPNS and patients with benign SPNs. â–¡, statistical significance between patients with benign SPNs and healthy controls.