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Table 3 ORs of breast cancer associated with intake of dietary antioxidants, NECSS, Canada, 1994-1997

From: Antioxidants and breast cancer risk- a population-based case-control study in Canada

 

Pre-menopausal

Post-menopausal

Nutrient

Quartiles of intake

Quartiles of intake

 

Q1*

Q2

Q3

Q4

p for

Q1*

Q2

Q3

Q4

p for

  

OR† (95% CI)

OR† (95% CI)

OR† (95% CI)

trend

 

OR†† (95% CI)

OR†† (95% CI)

OR†† (95% CI)

trend

Carotenoids

          

Beta-carotene (μg/wk)#

1.00

0.87 (0.65-1.15)

0.97 (0.73-1.28)

0.87 (0.65-1.17)

0.55

1.00

0.89 (0.72-1.10)

0.84 (0.68-1.04)

0.85 (0.68-1.06)

0.13

   Alpha-carotene (μg/wk)

1.00

0.82 (0.61-1.10)

0.95 (0.72-1.25)

0.85 (0.64-1.14)

0.46

1.00

0.86 (0.72-1.11)

0.89 (0.71-1.12)

0.92 (0.73-1.14)

0.53

   Lycopene (μg/wk)

1.00

0.97 (0.74-1.28)

0.99 (0.76-1.31)

0.88 (0.65-1.20)

0.53

1.00

1.15 (0.93-1.43)

1.20 (0.97-1.49)

1.21 (0.96-1.51)

0.14

   Lutein and Zeaxanthin (μg/wk)

1.00

0.92 (0.69-1.23)

1.08 (0.82-1.44)

0.82 (0.61-1.11)

0.41

1.00

0.81 (0.64-1.02)

0.94 (0.75-1.19)

0.94 (0.74-1.19)

0.86

   Beta cryptozanthin (μg/wk)

1.00

1.20 (0.89-1.60)

1.15 (0.87-1.53)

1.18 (0.86-1.60)

0.38

1.00

1.21 (0.98-1.50)

1.13 (0.90-1.40)

1.31 (1.04-1.65)

0.05

Vitamin C (mg/wk) #

1.00

1.00 (0.75-1.35)

1.21 (0.92-1.61)

0.87 (0.64-1.20)

0.89

1.00

1.13 (0.91-1.40)

1.14 (0.91-1.42)

1.24 (0.98-1.56)

0.09

Vitamin E (mg/wk) #

1.00

1.26 (0.93-1.70)

1.22 (0.89-1.68)

0.88 (0.62-1.25)

0.43

1.00

0.93 (0.75-1.15)

0.93 (0.74-1.17)

0.92 (0.73-1.17)

0.54

Selenium (μg/wk) #

1.00

1.22 (0.91-1.63)

1.23 (0.90-1.68)

1.10 (0.75-1.61)

0.58

1.00

1.21 (0.99-1.53)

1.10 (0.88-1.39)

1.09 (0.84-1.43)

0.73

Zinc (mg/wk) #

1.00

1.05 (0.78-1.41)

1.14 (0.83-1.57)

1.18 (0.79-1.77)

0.35

1.00

1.07 (0.85-1.35)

1.07 (0.84-1.36)

1.21 (0.91-1.71)

0.23

  1. * Reference category
  2. † Adjusted for age, province of residence, education, smoking pack years, alcohol consumption, number of live births, age at menarche, and total energy intake.
  3. †† Adjusted for age, province of residence, education, smoking pack years, alcohol consumption, BMI, recreational physical activity, number of live births, age at menarche, and total energy intake.
  4. # Also adjusted for years of taking antioxidants from supplementation.
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