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Table 3 ORs of breast cancer associated with intake of dietary antioxidants, NECSS, Canada, 1994-1997

From: Antioxidants and breast cancer risk- a population-based case-control study in Canada

  Pre-menopausal Post-menopausal
Nutrient Quartiles of intake Quartiles of intake
  Q1* Q2 Q3 Q4 p for Q1* Q2 Q3 Q4 p for
   OR† (95% CI) OR† (95% CI) OR† (95% CI) trend   OR†† (95% CI) OR†† (95% CI) OR†† (95% CI) trend
Carotenoids           
Beta-carotene (μg/wk)# 1.00 0.87 (0.65-1.15) 0.97 (0.73-1.28) 0.87 (0.65-1.17) 0.55 1.00 0.89 (0.72-1.10) 0.84 (0.68-1.04) 0.85 (0.68-1.06) 0.13
   Alpha-carotene (μg/wk) 1.00 0.82 (0.61-1.10) 0.95 (0.72-1.25) 0.85 (0.64-1.14) 0.46 1.00 0.86 (0.72-1.11) 0.89 (0.71-1.12) 0.92 (0.73-1.14) 0.53
   Lycopene (μg/wk) 1.00 0.97 (0.74-1.28) 0.99 (0.76-1.31) 0.88 (0.65-1.20) 0.53 1.00 1.15 (0.93-1.43) 1.20 (0.97-1.49) 1.21 (0.96-1.51) 0.14
   Lutein and Zeaxanthin (μg/wk) 1.00 0.92 (0.69-1.23) 1.08 (0.82-1.44) 0.82 (0.61-1.11) 0.41 1.00 0.81 (0.64-1.02) 0.94 (0.75-1.19) 0.94 (0.74-1.19) 0.86
   Beta cryptozanthin (μg/wk) 1.00 1.20 (0.89-1.60) 1.15 (0.87-1.53) 1.18 (0.86-1.60) 0.38 1.00 1.21 (0.98-1.50) 1.13 (0.90-1.40) 1.31 (1.04-1.65) 0.05
Vitamin C (mg/wk) # 1.00 1.00 (0.75-1.35) 1.21 (0.92-1.61) 0.87 (0.64-1.20) 0.89 1.00 1.13 (0.91-1.40) 1.14 (0.91-1.42) 1.24 (0.98-1.56) 0.09
Vitamin E (mg/wk) # 1.00 1.26 (0.93-1.70) 1.22 (0.89-1.68) 0.88 (0.62-1.25) 0.43 1.00 0.93 (0.75-1.15) 0.93 (0.74-1.17) 0.92 (0.73-1.17) 0.54
Selenium (μg/wk) # 1.00 1.22 (0.91-1.63) 1.23 (0.90-1.68) 1.10 (0.75-1.61) 0.58 1.00 1.21 (0.99-1.53) 1.10 (0.88-1.39) 1.09 (0.84-1.43) 0.73
Zinc (mg/wk) # 1.00 1.05 (0.78-1.41) 1.14 (0.83-1.57) 1.18 (0.79-1.77) 0.35 1.00 1.07 (0.85-1.35) 1.07 (0.84-1.36) 1.21 (0.91-1.71) 0.23
  1. * Reference category
  2. † Adjusted for age, province of residence, education, smoking pack years, alcohol consumption, number of live births, age at menarche, and total energy intake.
  3. †† Adjusted for age, province of residence, education, smoking pack years, alcohol consumption, BMI, recreational physical activity, number of live births, age at menarche, and total energy intake.
  4. # Also adjusted for years of taking antioxidants from supplementation.