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Table 5 Stratified analysis in 246 NPC patients with lung metastasis(es) alone at diagnosis or the first failure.

From: Factors determining the survival of nasopharyngeal carcinoma with lung metastasis alone: does combined modality treatment benefit?

  

PMS

OS

Variables

Cases

HR (95% CI)

P a

HR (95% CI)

P a

Age ≤ 45 years

  

0.004

 

0.005

   Chemo alone

90

1

 

1

 

   Chemo+local

40

0.484 (0.293-0.798)

 

0.485 (0.292-0.805)

 

Age > 45 years

  

0.005

 

0.006

   Chemo alone

92

1

 

1

 

   Chemo+local

24

0.434 (0.242-0.779)

 

0.451 (0.257-0.792)

 

DFI < 1 year

  

0.283

 

0.571

   Chemo alone

78

1

 

1

 

   Chemo+local

14

0.676 (0.332-1.380)

 

0.814 (0.400-1.656)

 

DFI = 1~3 years

  

0.008

 

0.005

   Chemo alone

59

1

 

1

 

   Chemo+local

27

0.460 (0.260-0.815)

 

0.429 (0.239-0.770)

 

DFI > 3 years

  

0.006

 

0.006

   Chemo alone

45

1

 

1

 

   Chemo+local

23

0.353 (0.168-0.739)

 

0.342 (0.160-0.730)

 
  1. Abbreviation: NPC, nasopharyngeal carcinoma; PMS, post-metastasis survival; OS, overall survival; HR, hazard ratio; 95% CI, 95% confidence interval; DFI, disease-free interval.
  2. a Cox proportional hazards analysis.