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Table 5 Stratified analysis in 246 NPC patients with lung metastasis(es) alone at diagnosis or the first failure.

From: Factors determining the survival of nasopharyngeal carcinoma with lung metastasis alone: does combined modality treatment benefit?

   PMS OS
Variables Cases HR (95% CI) P a HR (95% CI) P a
Age ≤ 45 years    0.004   0.005
   Chemo alone 90 1   1  
   Chemo+local 40 0.484 (0.293-0.798)   0.485 (0.292-0.805)  
Age > 45 years    0.005   0.006
   Chemo alone 92 1   1  
   Chemo+local 24 0.434 (0.242-0.779)   0.451 (0.257-0.792)  
DFI < 1 year    0.283   0.571
   Chemo alone 78 1   1  
   Chemo+local 14 0.676 (0.332-1.380)   0.814 (0.400-1.656)  
DFI = 1~3 years    0.008   0.005
   Chemo alone 59 1   1  
   Chemo+local 27 0.460 (0.260-0.815)   0.429 (0.239-0.770)  
DFI > 3 years    0.006   0.006
   Chemo alone 45 1   1  
   Chemo+local 23 0.353 (0.168-0.739)   0.342 (0.160-0.730)  
  1. Abbreviation: NPC, nasopharyngeal carcinoma; PMS, post-metastasis survival; OS, overall survival; HR, hazard ratio; 95% CI, 95% confidence interval; DFI, disease-free interval.
  2. a Cox proportional hazards analysis.