Skip to main content

Table 4 Prognostic variables of 246 NPC patients with lung metastasis(es) alone at diagnosis or the first failure.

From: Factors determining the survival of nasopharyngeal carcinoma with lung metastasis alone: does combined modality treatment benefit?

 

Post-metastasis survival

 

Overall survivall

Variables

Univariate Analysis

P a

Multivariate Analysis

P a

Univariate Analysis

P a

Multivariate Analysis

P a

Age

1.485 (1.097-2.010)

0.010

1.537 (1.038-2.277)

0.032

1.734 (1.277-2.355)

< 0.001

1.424 (1.027-1.974)

0.034

Sex

1.018 (0.712-1.458)

0.921

-

-

1.022 (0.714-1.463)

0.905

-

-

T classification

1.298 (0.948-1.778)

0.104

-

-

1.774 (1.281-2.456)

0.001

1.326 (0.936-1.876)

0.112

N classification

1.224 (0.809-1.852)

0.339

-

-

1.758 (1.150-2.688)

0.009

1.395 (0.905-2.150)

0.131

M classification

0.938 (0.625-1.408)

0.758

-

-

3.010 (1.965-4.612)

< 0.001

1.290 (0.766-2.172)

0.338

EBV VCA-lgA

1.490 (1.033-2.148)

0.033

1.342 (0.920-1.958)

0.127

1.348 (0.935-1.942)

0.110

-

-

EBV EA-lgA

1.171 (0.803-1.710)

0.412

-

-

1.199 (0.820-1.753)

0.349

-

-

DFI

0.818 (0.676-0.991)

0.040

1.019 (0.796-1.304)

0.881

0.326 (0.263-0.404)

< 0.001

0.379 (0.294-0.490)

< 0.001

Metastasis site

1.846 (1.357-2.512)

< 0.001

1.295 (0.779-2.153)

0.319

1.964 (1.439-2.682)

< 0.001

1.561 (0.967-2.520)

0.068

Metastasis number

1.813 (1.295-2.539)

0.001

1.274 (0.705-2.301)

0.422

1.970 (1.403-2.768)

< 0.001

1.284 (0.761-2.097)

0.365

Metastasis size

0.952 (0.699-1.296)

0.754

-

-

0.689 (0.505-0.941)

0.019

0.922 (0.664-1.281)

0.629

Recurrence

1.785 (1.125-2.832)

0.014

1.429 (0.778-2.625)

0.250

1.197 (0.755-1.896)

0.444

-

-

Treatment modalityb

0.440 (0.302-0.641)

< 0.001

0.583 (0.355-0.960)

0.034

0.454 (0.321-0.660)

< 0.001

0.566 (0.374-0.857)

0.007

Chemotherapy cyclec

0.828 (0.612-1.122)

0.828

-

-

1.143 (0.842-1.552)

0.392

-

-

-Chemotherapy effectd

2.305 (1.016-5.228)

0.046

1.243 (0.511-3.026)

0.632

1.603 (0.708-3.627)

0.258

-

-

  1. Abbreviation: NPC, nasopharyngeal carcinoma; DFI, disease-free interval.
  2. a Cox proportional hazards analysis.
  3. b Chemotherapy alone vs. combined therapy;
  4. c chemotherapy cycle < 6 vs. chemotherapy cycle ≥ 6;
  5. d Complete remission vs. non-complete remission.
Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us