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Table 1 Growth of UV-induced B cell tumors in immune-deficient but not wild type mice

From: Induction of B-cell lymphoma by UVB Radiation in p53 Haploinsufficient Mice

Recipient Mice* Number of mice Number with tumor p‡
Rag2-/- 15 15 _
C57Bl/6 15 1 0.0001
UV-irradiated C57Bl/6† 15 2 0.0001
  1. * 2 × 106 tumor cells were injected into the subcutaneous space of the recipient mice. Tumor growth was monitored daily. Mice were sacrificed when the tumor volume exceeded 1 cm2.
  2. † 10 kJ/m2 UVB radiation, 3x per week for 12 weeks prior to tumor transplantation
  3. ‡ p values determined by Fisher's exact test comparing tumor growth in immune deficient Rag2-/- vs. growth in wild type or UV-irradiated wild type mice.
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BMC Cancer

ISSN: 1471-2407

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