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Table 2 SNPassoc results for previously identified and mucin SNPs in EPICOLON cohorts.

From: Case-control study for colorectal cancer genetic susceptibility in EPICOLON: previously identified variants and mucins

EPICOLON stages 1+2 (1,416 CRC cases and 1,424 controls)
ADH1C         
rs698 Controls % Cases % OR lower upper P-value
Codominant         
A/A 629 46.1 616 44.2 1.00    0.13565
A/G 610 44.7 620 44.4 1.04 0.89 1.22  
G/G 125 9.2 159 11.4 1.30 1.00 1.69  
Dominant         
A/A 629 46.1 616 44.2 1.00    0.29181
A/G-G/G 735 53.9 779 55.8 1.08 0.93 1.26  
Recessive         
A/A-A/G 1239 90.8 1236 88.6 1.00    0.05243
G/G 125 9.2 159 11.4 1.28 1.00 1.63  
Log-Additive         
0, 1, 2 1364 49.4 1395 50.6 1.10 0.98 1.24 0.09043
IL6         
rs1800795 Controls % Cases % OR lower upper P-value
Codominant         
G/G 593 42.7 586 41.7 1.00    0.7950
G/C 623 44.9 635 45.2 1.03 0.88 1.21  
C/C 172 12.4 184 13.1 1.08 0.85 1.37  
Dominant         
G/G 593 42.7 586 41.7 1.00    0.5862
G/C-C/C 795 57.3 819 58.3 1.04 0.90 1.21  
Recessive         
G/G-G/C 1216 87.6 1221 86.9 1.00    0.5763
C/C 172 12.4 184 13.1 1.07 0.85 1.33  
log-Additive         
0, 1, 2 1388 49.7 1405 50.3 1.04 0.93 1.16 0.5034
ARL11         
rs3803185 Controls % Cases % OR lower upper P-value
Codominant         
A/A 359 26.9 301 23.7 1.00    0.12263
A/G 686 51.4 666 52.4 1.15 0.95 1.39  
G/G 289 21.7 304 23.9 1.26 1.01 1.57  
Dominant         
A/A 359 26.9 301 23.7 1.00    0.06417
A/G-G/G 975 73.1 970 76.3 1.18 0.99 1.41  
Recessive         
A/A-A/G 1045 78.3 967 76.1 1.00    0.15480
G/G 289 21.7 304 23.9 1.14 0.95 1.37  
log-Additive         
0, 1, 2 1334 51.2 1271 48.8 1.12 1.00 1.25 0.04338
GALNTL2         
rs2102302 Controls % Cases % OR lower upper P-value
Codominant         
A/A 579 42.1 538 39.0 1.00    0.16056
A/G 607 44.1 624 45.3 1.11 0.94 1.30  
G/G 189 13.7 217 15.7 1.23 0.98 1.55  
Dominant         
A/A 579 42.1 538 39.0 1.00    0.0971
A/G-G/G 796 57.9 841 61.0 1.14 0.98 1.32  
Recessive         
A/A-A/G 1186 86.3 1162 84.3 1.00    0.14317
G/G 189 13.7 217 15.7 1.17 0.95 1.45  
log-Additive         
0, 1, 2 1375 49.9 1379 50.1 1.11 1.00 1.24 0.0558
  1. Significant P-values (< 0.05) are highlighted in bold.
  2. OR, odds ratio