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Figure 1 | BMC Cancer

Figure 1

From: A novel inhibitor of hypoxia-inducible factor-1α P3155 also modulates PI3K pathway and inhibits growth of prostate cancer cells

Figure 1

P3155 specifically inhibits hypoxic induction of luciferase expression in U251-HRE but not in U251-pGL3. U251-HRE and U251-pGL3 were seeded in 96-well optiplates and incubated under normoxic or hypoxic conditions in the presence or absence of the indicated concentrations (μmol/L) of P3155. Cells were treated for 24 h and then tested for luciferase expression. Results are expressed as percentage inhibition of luciferase levels induced under hypoxic conditions (equal to 100%). Data presented as the average ± SE of three independent experiments.

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BMC Cancer

ISSN: 1471-2407

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