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Figure 5 | BMC Cancer

Figure 5

From: A cyclopalladated complex interacts with mitochondrial membrane thiol-groups and induces the apoptotic intrinsic pathway in murine and cisplatin-resistant human tumor cells

Figure 5

Increase in cytosolic calcium induced by C7a. Calcium concentration was evaluated in B16F10-Nex2 cells incubated with regular or calcium-free buffer. (A) and (B) Representative fluorescence ratio (340/380) traces of single cells are shown after C7a (1 μM) addition at Image Zero in the presence (A) or absence of calcium in the buffer (B). (C) Histogram shows the media ± standard deviation of the fluorescence ratio at 340/380 in all cells analyzed. Normalized fluorescence value was determined before C7a addition and data were expressed as percentage in relation to the baseline. *, p < 0.05. The results are representative of 3 independent experiments.

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BMC Cancer

ISSN: 1471-2407

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