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Table 2 Univariate analysis: factors predicting overall survival

From: An intracellular targeted antibody detects EGFR as an independent prognostic factor in ovarian carcinomas

Parameter

n (%)

Overall survival

  

p-value (log rank)

HR (CI), p-value

Membranous EGFR

121 (100)

0.002

2.8 (1.4-5.6), 0.004

positive

44 (36.4)

  

negative

77 (63.6)

  

Cytoplasmic EGFR

121 (100)

0.79

0.9 (0.4-1.8), 0.79

positive

81 (66.9)

  

negative

40 (33.1)

  

Age at surgery (years)

121 (100)

0.003

2.8 (1.3-5.7), 0.004

< 60

73 (60.3)

  

≥ 60

48 (39.7)

  

Histological type

121 (100)

0.71

1.1 (0.7-1.9), 0.68

serous

80 (66.1)

  

non-serous

29 (24.0)

  

undifferentiated

12 (9.9)

  

FIGO stage

121 (100)

0.44

1.5 (0.9-2.5), 0.13

I

18 (14.9)

  

II

10 (8.3)

  

III

84 (69.4)

  

IV

9 (7.4)

  

Tumor stage

121 (100)

0.14

1.6 (0.9-2.9), 0.08

pT1

21 (17.3)

  

pT2

12 (10.0)

  

pT3

88 (72.7)

  

Nodal stage

96 (100)

0.05

2.7 (0.9-7.8), 0.06

pN0

46 (47.9)

  

pN1

50 (52.1)

  

Tumor grade

121 (100)

0.035

2.0 (1.1-3.5), 0.013

G1

19 (15.7)

  

G2

50 (41.3)

  

G3

52 (43.0)

  

Intraoperative residual tumor

88 (100)

0.0001

5.0 (1.9-13.0), 0.001

residual tumor < 2 cm

78 (88.6)

  

residual tumor ≥ 2 cm

10 (11.4)

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