Table 2 Comparisons of clinical and tumor characteristics by molecular subtypes of breast cancer, the Shanghai Breast Cancer Survival Study.

Mean age at diagnosis*

54.1(10.2)

52.3 (9.3)

53.4 (9.7)

53.5 (10.7)

53.1 (9.9)

0.03

Age at diagnosis

0.02

<30

3 (0.22)

2 (0.43)

1 (0.26)

4 (1.11)

1 (0.44)

30-39

47 (3.47)

21 (4.50)

16 (4.19)

22 (6.11)

9 (3.96)

40-49

556 (41.03)

201 (43.04)

138 (36.13)

134 (37.22)

99 (43.61)

50-59

364 (26.86)

148 (31.69)

125 (32.72)

97 (26.94)

60 (26.43)

60-69

230 (16.97)

63 (13.49)

70 (18.32)

67 (18.61)

39 (17.18)

≥70

155 (11.44)

32 (6.85)

32 (8.38)

36 (10.00)

19 (8.37)

Pre-menopausal

661 (48.78)

239 (51.18)

167 (43.72)

174 (48.33)

114 (50.22)

0.27

Family history of breast cancer

61 (4.50)

21 (4.50)

17 (4.45)

28 (7.78)

17 (7.49)

0.048

TNM stage

0

32 (2.36)

11 (2.36)

8 (2.09)

7 (1.94)

5 (2.20)

<0.01

I

473 (34.91)

124 (26.55)

91 (23.82)

98 (27.22)

85 (37.44)

IIa

452 (33.36)

165 (35.33)

135 (35.34)

122 (33.89)

71 (31.28)

IIb

240 (17.71)

98 (20.99)

88 (23.04)

76 (21.11)

47 (20.70)

III-IV

109 (8.04)

55 (11.78)

51 (13.35)

42 (11.67)

15 (6.61)

Tumor size, cm *

2.80 (1.91)

3.31 (3.03)

3.34 (2.26)

3.14 (1.57)

2.82 (1.73)

<0.01

Histologic grade

I

306 (22.58)

31 (6.64)

17 (4.45)

48 (13.33)

36 (15.86)

<0.01

II

736 (54.32)

217 (46.47)

140 (36.65)

106 (29.44)

113 (49.78)

III

219 (16.16)

159 (34.05)

190 (49.74)

175 (48.61)

60 (26.43)

Histologic type

Noninvasive**

41 (3.03)

20 (4.28)

18 (4.71)

10 (2.78)

7 (3.08)

<0.01

ILC NOS

142 (10.48)

23 (4.93)

8 (2.09)

18 (5.00)

24 (10.57)

IDC NOS

834 (61.55)

361 (77.30)

314 (82.20)

253 (70.28)

162 (71.37)

Special types

318 (23.47)

60 (12.85)

39 (10.21)

76 (21.11)

34 (14.98)