Patients' characteristics | No. cases | uPA | PAI-1 | No. casesa | uPAR-wt | uPAR-del4/5 |
---|---|---|---|---|---|---|
low/high | low/high | low/high | low/high | |||
Total | 78 | 77/76 | ||||
Sexb | P = 0.071 | P = 0.111 | P = 0.031 | P = 0.201 | ||
Male | 35 | 21/14 | 20/15 | 34/33 | 20/14 | 18/15 |
Female | 43 | 18/25 | 18/25 | 43 | 18/25 | 20/23 |
Histological subtypec, d | P = 0.135 | P = 0.037 | P = 0.044 | P < 0.001 | ||
LS | 18 | 10/8 | 9/9 | 18 | 13/5 | 15/3 |
MFH | 17 | 6/11 | 8/9 | 16/15 | 6/10 | 7/8 |
FS | 3 | 1/2 | 0/3 | 3 | 1/2 | 1/2 |
RMS | 6 | 4/2 | 3/3 | 6 | 3/3 | 1/5 |
LMS | 17 | 6/11 | 6/11 | 17 | 6/11 | 4/13 |
NS | 7 | 5/2 | 5/2 | 7 | 5/2 | 5/2 |
Syn | 10 | 7/3 | 8/2 | 10 | 4/6 | 5/5 |
Tumor gradec | P = 0.149 | P = 0.017 | P = 0.178 | P = 0.003 | ||
I | 15 | 7/8 | 6/9 | 15 | 8/7 | 9/6 |
II | 32 | 20/12 | 21/11 | 32 | 17/15 | 19/13 |
III | 31 | 12/19 | 12/19 | 30/29 | 13/17 | 10/19 |
Tumor stagec | P = 0.431 | P = 0.111 | P = 0.483 | P = 0.031 | ||
I | 13 | 6/7 | 5/8 | 13 | 7/6 | 8/5 |
II | 31 | 19/12 | 20/11 | 31 | 16/15 | 18/13 |
III | 25 | 9/16 | 10/15 | 24/23 | 11/13 | 9/14 |
IV | 9 | 5/4 | 4/5 | 9 | 4/5 | 3/6 |
Complete resectionb | P = 0.056 | P = 0.304 | P = 0.437 | P = 0.200 | ||
Radical (R0) | 52 | 22/30 | 24/28 | 52/51 | 23/29 | 24/27 |
Not radical (R1) | 26 | 17/9 | 15/11 | 25 | 15/10 | 14/11 |
Tumor localizationc | P = 0.197 | P = 0.071 | P = 0.098 | P = 0.394 | ||
Extremities | 49 | 22/27 | 22/27 | 48/47 | 19/29 | 21/26 |
Trunk wall | 6 | 4/2 | 3/3 | 6 | 5/1 | 3/3 |
Head/neck | 2 | 2/0 | 2/0 | 2 | 2/0 | 1/1 |
Abdomen/retroperitoneum | 21 | 11/10 | 12/9 | 21 | 12/9 | 13/8 |
Patient follow-upb | P = 0.405 | P = 0.645 | P = 0.748 | P = 0.688 | ||
Alive | 36 | 15/21 | 18/18 | 36/35 | 18/18 | 18/17 |
Dead | 42 | 24/18 | 21/21 | 41 | 20/21 | 20/21 |